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Hepatomegaly is enlargement of the liver. [4] It is a non-specific medical sign , having many causes, which can broadly be broken down into infection , hepatic tumours , and metabolic disorder . Often, hepatomegaly presents as an abdominal mass .
Hepatomegaly with enlarged liver visible in red crosshairs and extending downward. Impairment in the liver's ability to perform gluconeogenesis leads to clinically apparent hepatomegaly . Without this process, the body is unable to liberate glycogen from the liver and convert it into blood glucose, leading to an accumulation of stored glycogen ...
Glycogenic hepatopathy [1] (also known as Mauriac syndrome [2]) is a rare complication of type 1 diabetes characterized by extreme liver enlargement due to glycogen deposition, along with growth failure and delayed puberty. It occurs in some children and adolescents with type 1 diabetes irrespective of their glycemic control.
Hepatomegaly: Medical imaging: Longitudinal axis > 15.5 cm at the hepatic midline, or > 16.0 cm at the midclavicular line [14] Autopsy: Weight over upper limit of standard reference range, of 1,860 g (4.10 lb) in men [12] and 1,770 g (3.90 lb) in women. [13] Lymph nodes: Lymphadenopathy: Generally 10 mm [15] [16
Clinical examination usually reveals hepatomegaly. Muscular disease, including hypotonia and cardiomyopathy, usually occurs later. The liver pathology typically regresses as the individual enters adolescence, as does splenomegaly, should the individual so develop it. [2]
HuffPost looked at how killers got their guns for the 10 deadliest mass shootings over the past 10 years. To come up with the list, we used Mother Jones’ database, which defines mass shootings as “indiscriminate rampages in public places” that kill three or more people.
Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease.
Diabetes mellitus type 2 is a disease characterized by chronically elevated blood glucose levels, even when fasting. [17] The rapidly rising prevalence of type 2 diabetes, along with its strong correlation to heart disease and other health complications has rendered it an area of intense research with an urgent need for treatment options. [17]