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In Uruguay, President Jose Mujica signed legislation to legalize recreational cannabis in December 2013, making Uruguay the first country in the modern era to legalize the substance. In August 2014, Uruguay legalized growing up to six plants at home, as well as the formation of growing clubs, and a state-controlled marijuana dispensary regime.
Mechoulam initiated a research project that led to the isolation of the first described endocannabinoid anandamide (N-arachidonoyl-ethanolamine, AEA) in 1992. [ 21 ] [ 7 ] Anandamide, which is a fatty acid derivative, differs in its structure from the plant cannabinoid, and has the same activity profile as THC. [ 29 ]
The genus Cannabis was first classified using the "modern" system of taxonomic nomenclature by Carl Linnaeus in 1753, who devised the system still in use for the naming of species. [64] He considered the genus to be monotypic, having just a single species that he named Cannabis sativa L. [ a 1 ] Linnaeus was familiar with European hemp, which ...
Marihuana prensada ('pressed marijuana') is a cannabis-derived product widespread among the lower classes of South America, [185] especially from the 90s. Locally it is known as "paraguayo" or "paragua", since its main producer is Paraguay. [186] Marijuana is dried and mixed with binding agents that make it toxic and highly harmful to health. [187]
They discovered that Rastafarians had unusually low glaucoma rates and local fishermen were washing their eyes with cannabis extract in the belief that it would improve their sight. Lockhart and West developed, and in 1987 gained permission to market, the pharmaceutical Canasol: one of the first cannabis extracts
The old northern varieties of hemp did not contain the narcotic THC; and the 2nd millennium was probably the first time that enough people were travelling back and forth between Iran (where it grew) and eastern Europe that they could spread a habit, along with its source, the THC-bearing hemp. And the early 1st-millennium B.C. is just when we ...
Anandamide was discovered by Raphael Mechoulam and fellow coworkers in 1992. This was the first marijuana-like substance produced by the human body to be observed. By examining a pig brain and canine gut, they were able to isolate ANA using mass spectrometry and nuclear magnetic resonance spectroscopy. [7]
Randall, who had discovered that cannabis relieved the symptoms of his glaucoma, employed a medical necessity defense at trial to justify his use of the drug. [95] The charges against Randall were dismissed, and as a result of an ensuing petition filed with the FDA, Randall became the first person to receive cannabis from the federal government ...