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Progressive supranuclear palsy (PSP) is a late-onset neurodegenerative disease involving the gradual deterioration and death of specific volumes of the brain. [ 1 ] [ 2 ] The condition leads to symptoms including loss of balance , slowing of movement , difficulty moving the eyes , and cognitive impairment . [ 1 ]
Cerebral palsy, a neural disorder caused by intracranial lesions; Conjugate gaze palsy, a disorder affecting the ability to move the eyes; Erb's palsy, also known as brachial palsy, involving paralysis of an arm; Spinal muscular atrophy, also known as wasting palsy; Progressive supranuclear palsy, a degenerative disease
Progressive supranuclear palsy (PSP) is a type of tauopathy, but the cause is not yet discovered. For PSP unusual phosphorylation for tau protein causes vital protein filaments in the nerve cells to destruct, a phenomenon called "neurofibrillary" degeneration.
PSP has been all over the news—here's what to know about it.
Cerebral aneurysm; Cerebral arteriosclerosis; Cerebral atrophy; Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy; Cerebral dysgenesis–neuropathy–ichthyosis–keratoderma syndrome; Cerebral gigantism; Cerebral palsy; Cerebral vasculitis; Cerebrospinal fluid leak; Cervical spinal stenosis; Charcot ...
Corticobasal degeneration (CBD) is a rare neurodegenerative disease involving the cerebral cortex and the basal ganglia. [1] CBD symptoms typically begin in people from 50 to 70 years of age, and typical survival before death is eight years.
For this study, scientists recruited study participants with mild cognitive impairment, progressive supranuclear palsy, Parkinson’s spectrum disorder, and Alzheimer’s disease dementia, as well ...
Additional features include bradykinesia, early-onset postural instability, increased rigidity in axial muscles, dysautonomia, alien limb syndrome, supranuclear gaze palsy, apraxia, involvement of the cerebellum including the pyramidal cells, and in some instances significant cognitive impairment.
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