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The olfactory bulb is supported and protected by the cribriform plate of the ethmoid bone, which in mammals separates it from the olfactory epithelium, and which is perforated by olfactory nerve axons. The bulb is divided into two distinct structures: the main olfactory bulb and the accessory olfactory bulb.
In the olfactory bulb, the ORNs synapse with termination in the glomeruli. [6] Each glomerulus receives input from olfactory receptor neurons expressing only one type of olfactory receptor. The glomerular activation patterns within the olfactory bulb are thought to represent the quality of the odor being detected.
The olfactory system, is the sensory system used for the sense of smell (olfaction). Olfaction is one of the special senses directly associated with specific organs. Most mammals and reptiles have a main olfactory system and an accessory olfactory system.
The Lady and the Unicorn, a Flemish tapestry depicting the sense of smell, 1484–1500. Musée national du Moyen Âge, Paris.. Early scientific study of the sense of smell includes the extensive doctoral dissertation of Eleanor Gamble, published in 1898, which compared olfactory to other stimulus modalities, and implied that smell had a lower intensity discrimination.
Unlike the main olfactory bulb that sends neuronal signals to the olfactory cortex, the VNO sends neuronal signals to the accessory olfactory bulb and then to the amygdala, BNST, and ultimately hypothalamus. Since the hypothalamus is a major neuroendocrine center (affecting aspects of reproductive physiology and behavior as well as other ...
Mitral cells are a neuronal cell type in the mammalian olfactory bulb, distinguished by the position of their somata located in an orderly row in the mitral cell layer of the bulb. [4] They typically have a single primary dendrite, which they project into a single glomerulus in the glomerular layer, and a few lateral dendrites that project ...
The AON connects the olfactory processing centres of both hemispheres. [1] It is involved in the sense of smell (olfaction), and has influence on other olfactory areas including the olfactory bulb and the piriform cortex. [2] [3] The AON is one of the major secondary structures of olfaction. [4]
This allows the granule cells to regulate the processing of the sensory input in the olfactory bulb. [21] The olfactory bulb transmits smell information from the nose to the brain, and is thus necessary for a proper sense of smell. Granule cells in the olfactory bulb have also been found to be important in forming memories linked with scents. [22]