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The lungs are the most radiosensitive organ, and radiation pneumonitis can occur leading to pulmonary insufficiency and death (100% after exposure to 50 Gray of radiation), in a few months. Radiation pneumonitis is characterized by: [10] Loss of epithelial cells; Edema; Inflammation; Occlusions of airways, air sacs and blood vessels; Fibrosis
The human body can survive relatively high blast overpressure without experiencing barotrauma. A 5 psi blast overpressure will rupture eardrums in about 1% of subjects, and a 45 psi overpressure will cause eardrum rupture in about 99% of all subjects. The threshold for lung damage occurs at about 15 psi blast overpressure.
In general, surrounding a bomb with denser media, such as water, absorbs more energy and creates more powerful shock waves while at the same time limiting the area of its effect. When a nuclear weapon is surrounded only by air, lethal blast and thermal effects proportionally scale much more rapidly than lethal radiation effects as explosive ...
Damage of the lungs reduces the surface for oxygen uptake from the air, reducing the amount of the oxygen delivered to the brain. Tissue destruction initiates the synthesis and release of hormones or mediators into the blood which, when delivered to the brain, change its function.
The normal relaxed state of the lung and chest is partially empty. Further exhalation requires muscular work. Inhalation is an active process requiring work. [4] Some of this work is to overcome frictional resistance to flow, and part is used to deform elastic tissues, and is stored as potential energy, which is recovered during the passive process of exhalation, Tidal breathing is breathing ...
A thermonuclear weapon, fusion weapon or hydrogen bomb (H bomb) is a second-generation nuclear weapon design.Its greater sophistication affords it vastly greater destructive power than first-generation nuclear bombs, a more compact size, a lower mass, or a combination of these benefits.
For a given lung volume, the transpulmonary pressure is equal and opposite to the elastic recoil pressure of the lung. The transpulmonary pressure vs volume curve of inhalation (usually plotted as volume as a function of pressure) is different from that of exhalation, the difference being described as hysteresis. Lung volume at any given ...
The actual values in the lung vary depending on the position within the lung. If taken as a whole, the typical value is approximately 0.8. [4] Because the lung is centered vertically around the heart, part of the lung is superior to the heart, and part is inferior. This has a major impact on the V/Q ratio: [5] apex of lung – higher; base of ...