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These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30] In the EPC trial, at a median follow-up of 7.4 years, breast pain and gynecomastia respectively occurred in 73.6% and 68.8% of men treated with 150 mg/day bicalutamide ...
There were concerns that access to birth control pills would reduce condom use, and thereby increase STI rates. There were also concerns about the medication's side effects. In 1999, low dose forms of the pill were approved by the Clinic of Japan Family Planning Association, coinciding with the acceptance of the erectile dysfunction drug Viagra ...
As will all birth control medications, certain side effects may occur from taking the hormonal supplements. Changes in menstrual bleeding may occur, such as a lighter flow or complete stop to the regular monthly menses, or abnormal bleeding throughout the cycle.
Chlormadinone acetate (CMA), sold under the brand names Belara, Gynorelle, Lutéran, and Prostal among others, is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy, as a component of menopausal hormone therapy, in the treatment of gynecological disorders, and in the treatment of androgen-dependent conditions like enlarged prostate and prostate ...
The availability of the birth control pill in Japan is a highly contentious issue due to the government's concern for its many potentially negative systemic side effects and worry that it may contribute, through lack of condom use, to a rise of HIV. [11] While the pill is now available, usage continues to be lower than many other countries.
Side effects of estradiol valerate include breast tenderness, breast enlargement, nausea, headache, and fluid retention. [15] [13] [14] Estradiol valerate is an estrogen and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. [5] [4] [16] It is an estrogen ester and a prodrug of estradiol in the body.
Progestogen-only pills may also be prescribed for individuals wanting an oral form of birth control but do not wish to use estrogen-containing methods due to medical contraindications, intolerable side effects, or personal preference. [8]
[17] [4] However, it is thought that the antiandrogenic activity of CPA may only be significant at higher doses than are present in birth control pills. [4] [19] Both EE and CPA have antigonadotropic effects and act as contraceptives in women by suppressing ovulation. [17]
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