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  2. 5-Hydroxytryptophan - Wikipedia

    en.wikipedia.org/wiki/5-Hydroxytryptophan

    5-HTP is produced from the amino acid tryptophan through the action of the enzyme tryptophan hydroxylase. Tryptophan hydroxylase is one of the biopterin-dependent aromatic amino acid hydroxylases. Production of 5-HTP is the rate-limiting step in 5-HT (serotonin) synthesis. 5-HTP is normally rapidly converted to 5-HT by amino acid decarboxylase. [1]

  3. Tryptophan hydroxylase - Wikipedia

    en.wikipedia.org/wiki/Tryptophan_hydroxylase

    Tryptophan hydroxylase (TPH) is an enzyme (EC 1.14.16.4) involved in the synthesis of the monoamine neurotransmitter serotonin. Tyrosine hydroxylase, phenylalanine hydroxylase, and tryptophan hydroxylase together constitute the family of biopterin-dependent aromatic amino acid hydroxylases.

  4. Anaphrodisiac - Wikipedia

    en.wikipedia.org/wiki/Anaphrodisiac

    The amino acid 5-HTP, or 5-hydroxytryptophan, has been anecdotally reported to be a mild anaphrodisiac, as has the serotonergic empathogen MDMA, popularly known as "ecstasy". However, systematic study of these chemicals is lacking, due to the off-patent nature of 5-HTP, and the legal control of MDMA.

  5. α-Methyl-5-hydroxytryptophan - Wikipedia

    en.wikipedia.org/wiki/Α-methyl-5-hydroxytryptophan

    α-Methyl-5-hydroxytryptophan (α-Me-5-HTP) is a synthetic tryptamine derivative, an artificial amino acid, and a prodrug of α-methylserotonin. [ 1 ] [ 2 ] It is the α- methylated derivative of 5-hydroxytryptophan (5-HTP), while αMS is the α-methylated analogue of serotonin .

  6. Oxitriptan - Wikipedia

    en.wikipedia.org/wiki/Oxitriptan

    MDMA is an empathogenic-entactogenic and serotonergic psychotropic drug used primarily for recreational, though sometimes also therapeutic, purposes.Among users of MDMA, the serotonergic effects of the drug are often of particular interest and concern: After consuming MDMA, serotonin concentrations are greatly reduced in the brain. 5-HTP is necessary for serotonin production and its ...

  7. Tetrahydrobiopterin - Wikipedia

    en.wikipedia.org/wiki/Tetrahydrobiopterin

    Tetrahydrobiopterin (BH 4, THB), also known as sapropterin (), [5] [6] is a cofactor of the three aromatic amino acid hydroxylase enzymes, [7] used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the ...

  8. Griffonia simplicifolia - Wikipedia

    en.wikipedia.org/wiki/Griffonia_simplicifolia

    [3] [4] 5-Hydroxytryptophan is an important building block for the human body to form serotonin, a neurotransmitter. [5] In one "randomized, double-blind, placebo-controlled trial" in 2010 Griffonia simplicifolia extract, was administered via oral spray to twenty overweight females resulting in increased satiety.

  9. 5-Hydroxyindoleacetaldehyde - Wikipedia

    en.wikipedia.org/wiki/5-Hydroxyindoleacetaldehyde

    5-Hydroxyindoleacetaldehyde (5-HIAL), also known as 5-hydroxytryptaldehyde or as serotonin aldehyde, is an inactive metabolite and metabolic intermediate of the monoamine neurotransmitter serotonin (5-hydroxytryptamine; 5-HT). [2] [3] [1] 5-HIAL is formed from serotonin by oxidative deamination via monoamine oxidase (MAO).

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