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2. Thyroglobulin - Wikipedia

   en.wikipedia.org/wiki/Thyroglobulin

   Thyroglobulin (Tg) is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Tg is secreted and accumulated at hundreds of grams per litre in the extracellular compartment of the thyroid follicles, accounting for approximately half of the protein content of the thyroid gland ...

3. Antithyroid autoantibodies - Wikipedia

   en.wikipedia.org/wiki/Antithyroid_autoantibodies

   Antithyroid autoantibodies (or simply antithyroid antibodies) are autoantibodies targeted against one or more components on the thyroid.The most clinically relevant anti-thyroid autoantibodies are anti-thyroid peroxidase antibodies (anti-TPO antibodies, TPOAb), thyrotropin receptor antibodies (TRAb) and thyroglobulin antibodies (TgAb).

4. Thyroxine-binding globulin - Wikipedia

   en.wikipedia.org/wiki/Thyroxine-binding_globulin

   Thyroxine-binding globulin (TBG) is a globulin protein encoded by the SERPINA7 gene in humans. TBG binds thyroid hormones in circulation.It is one of three transport proteins (along with transthyretin and serum albumin) responsible for carrying the thyroid hormones thyroxine (T 4) and triiodothyronine (T 3) in the bloodstream.

5. Graves' disease - Wikipedia

   en.wikipedia.org/wiki/Graves'_disease

   The TSHr is expressed on the thyroid follicular cells of the thyroid gland (the cells that produce thyroid hormone), and the result of chronic stimulation is an abnormally high production of T3 and T4. This, in turn, causes the clinical symptoms of hyperthyroidism, and the enlargement of the thyroid gland visible as goiter.

6. Thyroid hormones - Wikipedia

   en.wikipedia.org/wiki/Thyroid_hormones

   Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. [36] Thyroxine is produced by attaching iodine atoms to the ring structures of this protein's tyrosine residues; thyroxine (T 4 ) contains four iodine atoms, while triiodothyronine (T 3 ), otherwise ...

7. Computed tomography of the thyroid - Wikipedia

   en.wikipedia.org/wiki/Computed_tomography_of_the...

   In cases of elevated thyroglobulin with negative neck US and iodine whole body scintigraphy (WBS), fluorodeoxyglucose (FDG) positron emission tomography (PET) is the next modality of choice. Dedifferentiated thyroid carcinoma usually has avid FDG-PET uptake and a negative radioiodine scan typically does not respond to RAI therapy and has a ...

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9. Papillary thyroid cancer - Wikipedia

   en.wikipedia.org/wiki/Papillary_thyroid_cancer

   Thyroglobulin can be used as a tumor marker for well-differentiated papillary thyroid cancer. [7] [8] HBME-1 staining may be useful for differentiating papillary carcinomas from follicular carcinomas; in papillary lesions it tends to be positive.