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A cutaneous myxoma, or superficial angiomyxoma, consists of a multilobulated myxoid mass containing stellate or spindled fibroblasts with pools of mucin forming cleft-like spaces. There is often a proliferation of blood vessels and an inflammatory infiltrate.
A myxoma is a rare benign tumor of the heart. Myxomata are the most common primary cardiac tumor in adults, and are most commonly found within the left atrium near the valve of the fossa ovalis. Myxoma may also develop in the other heart chambers. [1] The tumor is derived from multipotent mesenchymal cells. [1]
Differential diagnosis includes periungual and subungual fibroma, acquired digital fibrokeratoma, superficial angiomyxoma, myxoid neurofibroma, dermal mucinosis, sclerosing perineuroma, low grade fibromyxoid sarcoma, myxoid dermatofibrosarcoma protuberans, fibroma of tendon sheath, giant cell tumour, glomus tumour, fibrous histiocytoma ...
A myxoid tumor is a connective tissue tumor with a "myxoid" background, composed of clear, mucoid substance. [1]Atrial myxoma. This tumoral phenotype is shared by many tumoral entities:
Myxoma is a rare, benign stromal tumor of mesenchymal origin often confused with other conjunctival stromal tumors. Conjunctival myxomas are thought to originate in Tenon's capsule and can masquerade as conjunctival lymphoma , lymphangioma , ocular surface squamous neoplasia (OSSN), or amelanotic melanoma .
Although it is a benign tumour and does not invade neighbouring tissues, it has a tendency to recur after surgical excision so it is termed "aggressive". Recurrence can occur as early as six months from initial resection.
The spotty skin pigmentation and lentigines occur most commonly on the face, especially on the lips, eyelids, conjunctiva and oral mucosa. [3] Cardiac myxomas may lead to embolic strokes and heart failure [4] and may present with fever, joint pain, shortness of breath, diastolic rumble and tumor plop.
The odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue associated with tooth formation. [1] As a myxoma , this tumor consists mainly of spindle shaped cells and scattered collagen fibers distributed through a loose, mucoid material.