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4-Hydroxybenzoic acid, also known as p-hydroxybenzoic acid (PHBA), is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid.It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar organic solvents such as alcohols and acetone. 4-Hydroxybenzoic acid is primarily known as the basis for the preparation of its esters, known as parabens ...
4-Hydroxybenzoic acid 4-O-glucoside is a glucoside of p-hydroxybenzoic acid. It can be found in mycorrhizal (Picea abies-Lactarius deterrimus and Picea abies-Laccaria amethystina) and non-mycorrhizal roots of Norway spruces (Picea abies). [1] The enzyme 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase can be found in the pollen of Pinus ...
Mometasone, also known as mometasone furoate, is a steroid (specifically, a glucocorticoid) medication used to treat certain skin conditions, hay fever, and asthma. [ 10 ] [ 11 ] [ 12 ] Specifically it is used to prevent rather than treat asthma attacks. [ 10 ]
Monohydroxybenzoic acid may refer to any of three isomeric phenolic acids: Salicylic acid (2-hydroxybenzoic acid, o-hydroxybenzoic acid) 3-Hydroxybenzoic acid (m-hydroxybenzoic acid) 4-Hydroxybenzoic acid (p-hydroxybenzoic acid) Monohydroxybenzoic acids can be degraded by microbes. [1]
Hydroxybenzoic acid may refer to several related chemical compounds: 2-Hydroxybenzoic acid (salicylic acid, o -hydroxybenzoic acid) 3-Hydroxybenzoic acid ( m -hydroxybenzoic acid)
4,4′-Dihydroxybenzophenone is prepared by the rearrangement of p-hydroxyphenylbenzoate: HOC 6 H 4 CO 2 C 6 H 5 → (HOC 6 H 4) 2 CO. Alternatively, p-hydroxybenzoic acid can be converted to p-acetoxybenzoyl chloride. This acid chloride reacts with phenol to give, after deacetylation, 4,4′-dihydroxybenzophenone.
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By using potassium hydroxide, 4-hydroxybenzoic acid is accessible, an important precursor for the versatile paraben class of biocides used e.g. in personal care products. The methodology is also used in the industrial synthesis of 3-hydroxy-2-naphthoic acid; the regiochemistry of the carboxylation in this case is sensitive to temperature. [6]