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A review for Boston Magazine called Sinclair "one of science's most controversial figures" and said many in the scientific community were skeptical of claims he made about human longevity. University of Alabama biology professor Steven N. Austad said, "David is a good friend, but I do think he's been guilty of making excessive claims."
David Andrew Sinclair AO (born June 26, 1969) is an Australian-American biologist and academic known for his research on aging and epigenetics. Sinclair is a professor of genetics at Harvard Medical School and the founding director of the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging at Harvard.
Guarente's rivalry with Sinclair, which began in 2002 when Sinclair challenged Guarante's description of how sir2 might be involved in aging at a scientific meeting at Cold Spring Harbor Laboratory, was the subject of an article in Science in 2004. [20] In 2014 Guarente co-founded the dietary supplement company Elysium Health. [13] [21]
Savannah Rep's most recent production, 'The Lifespan of a Fact,' based upon the real-life struggle between an earnest fact-checker and celebrated essayist, confronts the nature of truth.
David Sinclair and Rachel Drake shattered records in winning the men's and women's titles in the 62nd annual JFK 50 Mile ultramarathon on Saturday. Sinclair, 32, of South Burlington, Vermont, took ...
2007 Extension of mouse lifespan via deletion of insulin receptor in the brain. [30] [74] 2007 The book Ending Aging written by Aubrey de Grey and his research assistant Michael Rae. 2007 First evidence that a pharmacological agent (namely, metformin) at a certain dosage is capable to increase the lifespan of mice. [30] [75]
A 2009 review of longevity research noted: "Extrapolation from worms to mammals is risky at best, and it cannot be assumed that interventions will result in comparable life extension factors. Longevity gains from dietary restriction, or from mutations studied previously, yield smaller benefits to Drosophila than to nematodes, and smaller still ...
The Economic Value of Targeting Aging (with David Sinclair, Martin Ellison), Nature Aging 2021 [5] The Longevity Society and The Longevity Economy, The Lancet Healthy Longevity 2021 [ 6 ] [ 7 ] Government Debt Management: The Long AND the short of it (with Elisa Faraglia, Albert Marcet , Rigas Oikonomou), Review of Economic Studies 2019 [ 8 ]