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General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
The history of syphilis has been well studied, but the exact origin of the disease was the source of debate until archaeological and genetic evidence showed conclusively it originated in the Americas.
Meningeal syphilis (as known as syphilitic aseptic meningitis or meningeal neurosyphilis) is a chronic form of syphilis infection that affects the central nervous system. Treponema pallidum , a spirochate bacterium, is the main cause of syphilis, which spreads drastically throughout the body and can infect all its systems if not treated ...
The subject matter of delusions seems to reflect the current culture in a particular time and location. For example, in the US, during the early 1900s syphilis was a common topic, during the Second World War Germany, during the Cold War communists, and in recent years, technology has been a focus. [23]
In 2016, there were 27,814 reported cases of syphilis, primary and secondary, in the United States, a 17.6% increase from the previous year and a 74% increase from the reported cases in 2012. [22] Primary and secondary syphilis have a high correlation to an HIV-coinfection, particularly in men who have sex with men (MSM).
Congenital syphilis is syphilis that occurs when a mother with untreated syphilis passes the infection to her baby during pregnancy or at birth. [4] It may present in the fetus, infant, or later. [1] [5] Clinical features vary and differ between early onset, that is presentation before 2-years of age, and late onset, presentation after age 2 ...
Man with syphilis in German East Africa, c. early 1900s. Syphilis, a sexually transmitted infection, is a major danger to public health, particularly in developing countries, including those in sub-Saharan Africa. The disease, whose origin is contested amongst researchers, arrived in Africa no later than the 16th century. Since then, it has ...