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Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [1] Tentative evidence has found other antibiotics to be more effective, and therefore it is no longer generally recommended for second-degree (partial-thickness) burns, but is still ...
Silver sulfadiazine (SSD) is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [4] [21] It was discovered in the 1960s, [22] and was the standard topical antimicrobial for burn wounds for decades.
For use as adjunctive therapy for second- and third-degree burns to prevent infection, adults and children should apply topically to a thickness of approximately 1.6 mm to cleaned and debrided wound once or twice per day with a sterile gloved hand. The burned area should be covered with cream at all times. [citation needed]
Sulfadiazine is an antibiotic. [1] Used together with pyrimethamine , a dihydrofolate reductase inhibitor, it is the treatment of choice for toxoplasmosis, which is caused by a protozoan parasite . [ 3 ]
Certain sulfonamides (sulfadiazine or sulfamethoxazole) are sometimes mixed with the drug trimethoprim, which acts against dihydrofolate reductase. As of 2013, the Republic of Ireland is the largest exporter worldwide of sulfonamides, accounting for approximately 32% of total exports. [16]
I have seen this recommended in many cases, and used it myself in several, only one of which was an actual burn. Silver has been an excellent and safe microbial for thousands of years, and in every case I used it, I considered the healing miraculous. There is much more about Silver Sulfadiazine in the colloidal silver article than there is here.
[68] [69] Silver sulfadiazine (a type of antibiotic) is not recommended as it potentially prolongs healing time. [67] [70] There is insufficient evidence to support the use of dressings containing silver [71] or negative-pressure wound therapy. [72] Silver sulfadiazine does not appear to differ from silver containing foam dressings with respect ...
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