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Fibrates typically lower triglycerides by 20% to 50%. Level of the good cholesterol HDL is also increased. Fibrates may decrease LDL, though generally to a lesser degree than statins. Similar to statins, the risk of muscle damage exists. Nicotinic acid, like fibrates, is also well suited for lowering triglycerides by 20–50%. It may also lower ...
Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Outcomes (also known as AIM-HIGH) was a randomized control trial designed to assess the efficacy of niacin (extended-release) added to statin therapy in reducing cardiovascular events in patients with established atherosclerotic cardiovascular disease (ASCVD).
Dyslipidemia is a metabolic disorder characterized by abnormally high or low amounts of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood. [1] Dyslipidemia is a risk factor for the development of atherosclerotic cardiovascular diseases , [ 1 ] which include coronary artery disease ...
Xanthomas are a sign of high cholesterol or high triglycerides. Chest pain. Angina, or chest pain, can develop if your dyslipidemia has caused plaque to build up in your arteries, making it harder ...
A 2011 review reached similar conclusions, [25] and a 2012 review found benefits in both women and men. [26] A 2010 review concluded that treatment without history of cardiovascular disease reduces cardiovascular events in men but not women, and provides no mortality benefit in either sex. [27]
Xanthomas are a sign of high cholesterol or high triglycerides. Chest pain. Angina, or chest pain, can develop if your dyslipidemia has caused plaque to build up in your arteries, making it harder ...
While statins have strong evidence for reducing heart disease and death, there is evidence to suggest that fenofibrate also reduces the risk of heart disease and death. However, this seems only to apply to specific populations of people with elevated triglyceride levels and reduced high-density lipoprotein (HDL) cholesterol.
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