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Sodium butyrate is a compound with formula Na(C 3 H 7 COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of gene expression. [1] As such, it can be used in lab to bring about any of these effects.
Sodium phenylbutyrate, sold under the brand name Buphenyl among others, is a salt of an aromatic fatty acid, 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid. [7] The compound is used to treat urea cycle disorders , because its metabolites offer an alternative pathway to the urea cycle to allow excretion of excess nitrogen.
Recreational doses of 1–2 g generally provide a feeling of euphoria, and larger doses create deleterious effects such as reduced motor function and drowsiness. [9] The sodium salt of GHB has a salty taste. [31] Other salt forms such as calcium GHB and magnesium GHB have also been reported, [34] but the sodium salt is by far the most common.
In this treatment, a healthy individual donates their stool to be transplanted into an individual with dysbiosis. A less-invasive treatment option is the administration of butyrate—as oral supplements or enemas—which has been shown to be very effective in terminating symptoms of inflammation with minimal-to-no side-effects.
The US label for sodium oxybate has a black box warning because it is a central nervous system depressant (CNS depressant) and for its potential for abuse.Other potential adverse side effects include respiratory depression, seizures, coma, and death, especially when it is taken in combination with other CNS depressants such as alcohol.
β-Hydroxy β-methylbutyric acid [note 1] (HMB), otherwise known as its conjugate base, β-hydroxy β-methylbutyrate, is a naturally produced substance in humans that is used as a dietary supplement and as an ingredient in certain medical foods that are intended to promote wound healing and provide nutritional support for people with muscle wasting due to cancer or HIV/AIDS.
A Washington, D.C. man has been arrested for threatening flight attendants on a United Airlines plane traveling from Houston to New Jersey. Kedus Yacob Damtew, 38, was charged with one count of ...
Traveller's diarrhea's symptoms treated with an enema of sodium butyrate, organic acids, and A-300 silicon dioxide can be successfully decreased with lack of observed side effects. [ 7 ] Shigellosis treatment benefits from adjunct therapy with butyrate enemas, promoting healing of the rectal mucosa and inflammation, but not helping in clinical ...
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