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The United States Environmental Protection Agency (EPA) maintains and approves test methods, which are approved procedures for measuring the presence and concentration of physical, chemical and biological contaminants; evaluating properties, such as toxic properties, of chemical substances; or measuring the effects of substances under various conditions.
In recent decades, legislation aimed at the promotion of the 3Rs in regulatory testing have systematically been introduced into Europe. EU Directive 2010/63/EU [4] updates and replaces the 1986 Directive 86/609/EEC [5] on the protection of animals used for scientific purposes. The aim of the new Directive is to strengthen legislation, improve ...
The EPA's Science Advisory Board also pushed back against the proposal. [32] In September 2019, Wheeler signed a directive to prioritize efforts to reduce animal testing. Instead, the research should focus on new alternative test methods. The goal is to reduce its requests for, and funding of, mammal studies by 30% by 2025 and eliminate all ...
Its goal was "to develop, validate, and promote laboratory methods and techniques that don't use animal test subjects". [1] It was the first centre in Canada dedicated to non-animal testing and the promotion of human-relevant alternatives. [2] [3] The CCAAM ceased operations on May 31, 2024 due to budget cuts at the University of Windsor. [4]
Finnish Center for Alternative Methods (FICAM), since 2008 [111] FRANCOPA is the French platform dedicated to development, validation, and dissemination of alternative methods in animal testing. It was created on November 16, 2007. [112] The Italian Centro 3R was created in 2017. It is an interuniversity center dedicated to the promotion of the ...
People whose diabetes was recently diagnosed showed significant improvements in levels of HbA1c — a measurement of blood sugar — and their body weight. The study results appear in the Journal ...
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