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Medical Device Alert: DePuy ASR TM acetabular cups used in hip resurfacing arthroplasty and total hip replacement, Medicines and Healthcare products Regulatory Agency, MDA/2010/044, 25 May 2010; Medical Device Alert: All metal-on-metal (MoM) hip replacements, Medicines and Healthcare products Regulatory Agency, MDA/2012/008, 28 February 2012
Metallosis is the medical condition involving deposition and build-up of metal debris in the soft tissues of the body. [1]Metallosis has been known to occur when metallic components in medical implants, specifically joint replacements, abrade against one another. [1]
The analysis of 402,051 hip replacements showed that 6.2% of metal-on-metal hip implants had failed within five years, compared to 1.7% of metal-on-plastic and 2.3% of ceramic-on-ceramic hip implants. Each 1 mm (0.039 in) increase in head size of metal-on-metal hip implants was associated with a 2% increase in failure rate. [63]
On February 10, 2011, the U.S. FDA issued a patient advisory on metal-metal hip implants, stating it was continuing to gather and review all available information about metal-on-metal hip systems. [4] On June 27–28, 2012, an advisory panel met to decide whether to impose new standards.
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Orthopedic implant example seen with X-ray. An orthopedic implant is a medical device manufactured to replace a missing joint or bone, or to support a damaged bone. [1] The medical implant is mainly fabricated using stainless steel and titanium alloys for strength and the plastic coating that is done on it acts as an artificial cartilage. [2]
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