Search results
Results from the WOW.Com Content Network
View of left entorhinal cortex (red) from beneath the brain, with front of brain at top. Artist's rendering. The superficial layers – layers II and III – of EC project to the dentate gyrus and hippocampus: Layer II projects primarily to dentate gyrus and hippocampal region CA3; layer III projects primarily to hippocampal region CA1 and the subiculum.
The entorhinal cortex (EC) is a major part of the hippocampal formation of the brain, and is reciprocally connected with the hippocampus. [1]The hippocampal formation, which consists of the hippocampus, perirhinal cortex, the dentate gyrus, the subicular areas and the EC forms one of the most important parts of the limbic system.
The anterior part of the gyrus includes the perirhinal and entorhinal cortices [citation needed]. The term parahippocampal cortex is used to refer to an area that encompasses both the posterior parahippocampal gyrus and the medial portion of the fusiform gyrus [ citation needed ] .
The entorhinal cortex (EC) is a structure in the brain located in the medial temporal lobe.The EC is composed of six distinct layers. The superficial (outer) layers, which include layers I through III, are mainly input layers that receive signals from other parts of the EC, but also project to hippocampal structures via the perforant path.
In mice, the projection to CA1, and the subiculum all come primarily from EC layer III. [citation needed]According to Suh et al. (2011 Science 334:1415) the projection to CA3 and dentate gyrus in mice is primarily from layer II of entorhinal cortex, and forms a trisynaptic path with hippocampus (dentate gyrus to CA3 to CA1), distinguished from the direct (monosynaptic) perforant path from ...
Most external input comes from the adjoining entorhinal cortex, via the axons of the so-called perforant path. These axons arise from layer 2 of the entorhinal cortex (EC), and terminate in the dentate gyrus and CA3. There is also a distinct pathway from layer 3 of the EC directly to CA1, often referred to as the temporoammonic or TA-CA1 pathway.
There is no consensus concerning which brain regions are encompassed by the term, with some authors defining it as the dentate gyrus, the hippocampus proper and the subiculum; [2] and others including also the presubiculum, parasubiculum, and entorhinal cortex. [3]
The dentate gyrus (DG) is part of the hippocampal formation in the temporal lobe of the brain, which also includes the hippocampus and the subiculum.The dentate gyrus is part of the hippocampal trisynaptic circuit and is thought to contribute to the formation of new episodic memories, [1] [2] the spontaneous exploration of novel environments [2] and other functions. [3]