Search results
Results from the WOW.Com Content Network
The transient nature of these protein encounters complicates the study of quinary structure. Indeed, the interactions responsible for this upper level of protein organisation are weak and short-lived, and hence would not produce protein-protein complexes that could be isolated by conventional biochemical methods.
Protein quaternary structure [a] is the fourth (and highest) classification level of protein structure.Protein quaternary structure refers to the structure of proteins which are themselves composed of two or more smaller protein chains (also referred to as subunits).
Intermembrane lipid transfer protein VPS13B, also known as vacuolar protein sorting-associated 13B, and Cohen syndrome protein 1 is a protein that in humans is encoded by the VPS13B gene. It is a giant protein associated with the Golgi apparatus that is believed to be involved in post-Golgi apparatus sorting and trafficking. [ 5 ]
Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to its function.The structure of these molecules may be considered at any of several length scales ranging from the level of individual atoms to the relationships among entire protein subunits.
[3] [4] The sequence of a protein is unique to that protein, and defines the structure and function of the protein. The sequence of a protein can be determined by methods such as Edman degradation or tandem mass spectrometry. Often, however, it is read directly from the sequence of the gene using the genetic code.
English: Functional proteins have four levels of structural organization: 1) Primary Structure : the linear structure of amino acids in the polypeptide chain 2) Secondary Structure : hydrogen bonds between peptide group chains in an alpha helix or beta 3) Tertiary Structure : three-dimensional structure of alpha helixes and beta helixes folded
Similarly other biomolecules such as proteins, nucleic acids have four levels of structural arrangement: primary, secondary, tertiary, and quaternary structure. Primary structure is the linear sequence of nucleotides, secondary structure involves small local folding motifs, and tertiary structure is the 3D folded shape of nucleic acid molecule.
Each level in the hierarchy represents an increase in organisational complexity, with each "object" being primarily composed of the previous level's basic unit. [2] The basic principle behind the organisation is the concept of emergence —the properties and functions found at a hierarchical level are not present and irrelevant at the lower levels.