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Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity such as from a spinal cord injury or multiple sclerosis. [8] [9] It may also be used for hiccups and muscle spasms near the end of life, [9] and off-label to treat alcohol use disorder [10] [11] or opioid withdrawal symptoms. [12]
Between 1998 and 2007, 33 serious adverse drug or device reactions have been reported by RADAR investigators. The toxicities involved multiple biological system and included thrombotic thrombocytopenic purpura (TTP) (ticlopidine and clopidogrel), thromboembolism (thalidomide and lenalidomide), liver failure (gemtuzumab and nevirapine), hypersensitivity (drug eluting coronary arterial stents ...
The topic of baclofen for alcoholism is also before the NICE in the UK for consideration of the issuing of guidelines based on best evidence. Restricting the article to only published double blind studies does not capture the state of play in baclofen research, nor the controversy which is evidenced by the conflicting comments on this Talk board.
If the wikilink of that drug name redirects to another drug name (eg trade name to generic) then mention it on the list. If a trade name should redirect to a generic name of a drug page that hasn't been created yet, include the redirect mention in the list but don't create a page that redirects to a non-existant page.
The survey and its findings, however, didn’t show the whole picture. Robert Walker, an assistant professor at the university’s Center on Drug and Alcohol Research and a designer of the study, conceded that his team surveyed addicts early in their recovery. “You are probably seeing some honeymoon effect,” he said.
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There are a few foods you may want to skip on Thanksgiving if you're taking a GLP-1 medication such as Ozempic, dietician Kylie Bensley, founder of the women’s nutrition company, Sulinu, tells ...
CGP7930 was developed in Novartis and has been used extensively for scientific research. It has anxiolytic effects in animal studies, [ 6 ] [ 7 ] and has a synergistic effect with GABA B agonists such as baclofen and GHB , [ 8 ] [ 9 ] as well as reducing self-administration of alcoholic drinks and cocaine .