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No participants had received a COVID‑19 vaccine or been previously infected with COVID‑19. [12] The main outcome measured in the trial was the proportion of people who were hospitalized due to COVID‑19 or died due to any cause during 28 days of follow-up. [12] EPIC-HR started in July 2021, and completed in December 2021. [51]
This registry based, multi-center, multi-country data provide provisional support for the use of ECMO for COVID-19 associated acute hypoxemic respiratory failure. Given that this is a complex technology that can be resource intense, guidelines exist for the use of ECMO during the COVID-19 pandemic. [85] [86] [87]
The authors came to the conclusion that no further trials of hydroxychloroquine or chloroquine for treatment of COVID-19 should be carried out. [58] On 26 April 2021, in its amended clinical management protocol for COVID-19, the Indian Ministry of Health lists hydroxychloroquine for use in patients during the early course of the disease. [23]
The most recent COVID-19 vaccine should offer protection against the XEC variant, Russo says. “The most recent version of the vaccine seems to be reasonably well-matched,” he says.
The now-retracted study included 36 patients with COVID-19, including 20 who were said to have been treated with hydroxychloroquine and azithromycin, an antibiotic. The journal's review couldn't ...
Enanta Pharmaceuticals Inc (NASDAQ: ENTA) has dosed the first subject in its Phase 1 trial of EDP-235, a coronavirus 3CL protease inhibitor, specifically designed as a once-daily, oral treatment ...
A Phase 1/2 Study to Assess the Safety, Immunogenicity and Recommended Dose of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects. Mar 2021 – Jul 2022, Japan: GBP510 SK Bioscience Co. Ltd., GSK: South Korea, United Kingdom Subunit (Recombinant protein nanoparticle with adjuvanted with AS03) Phase III (4,000) [112]
Generally abbreviated to "P.R.N." or "PRN", pro re nata refers to the administration of prescribed medication whose timing is left to the patient (in the case of patient-controlled analgesia), nurse, or caregiver, as opposed to medication that is taken according to a fixed (primarily daily) schedule (a.k.a. "scheduled dosage").
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