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  2. Naproxen - Wikipedia

    en.wikipedia.org/wiki/Naproxen

    Naproxen's medical uses are related to its mechanism of action as an anti-inflammatory compound. [11] Naproxen is used to treat a variety of inflammatory conditions and symptoms that are due to excessive inflammation, such as pain and fever (naproxen has fever-reducing, or antipyretic, properties in addition to its anti-inflammatory activity). [11]

  3. ATC code M01 - Wikipedia

    en.wikipedia.org/wiki/ATC_code_M01

    ATC code M01 Anti-inflammatory and antirheumatic products is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.

  4. Pain ladder - Wikipedia

    en.wikipedia.org/wiki/Pain_ladder

    The WHO guidelines recommend prompt oral administration of drugs ("by the mouth") when pain occurs, starting, if the patient is not in severe pain, with non-opioid drugs such as paracetamol (acetaminophen) or aspirin, [1] with or without "adjuvants" such as non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2 inhibitors.

  5. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.

  6. Prostaglandin inhibitors - Wikipedia

    en.wikipedia.org/wiki/Prostaglandin_inhibitors

    Prostaglandin inhibitors are drugs that inhibit the synthesis of prostaglandin in human body. [1] There are various types of prostaglandins responsible for different physiological reactions such as maintaining the blood flow in stomach and kidney, regulating the contraction of involuntary muscles and blood vessels, and act as a mediator of inflammation and pain.

  7. Antiarthritics - Wikipedia

    en.wikipedia.org/wiki/Antiarthritics

    Despite the mechanism of action of acetaminophen is not completely understood, it appears to act on the COX pathway. It reduces COX activity by inhibiting the synthesis of prostaglandins in the central nervous system. [27] The reduction of COX activity contributes to its analgesic effects. [27]

  8. HuffPost Data

    projects.huffingtonpost.com

    Interactive maps, databases and real-time graphics from The Huffington Post

  9. Paracetamol - Wikipedia

    en.wikipedia.org/wiki/Paracetamol

    Paracetamol inhibits prostaglandin synthesis by reducing the active form of COX-1 and COX-2 enzymes. This occurs only when the concentration of arachidonic acid and peroxides is low. Under these conditions, COX-2 is the predominant form of cyclooxygenase, which explains the apparent COX-2 selectivity of paracetamol.

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