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Periods when gout symptoms are more severe are called gout flares or gout attacks. A gout flare comes on suddenly, and symptoms are often intense. This will most commonly happen at night.
What causes gout? The condition is caused by a buildup of uric acid in the body. Uric acid forms when the body breaks down purines, a chemical compound that cells use to form DNA and RNA.
The post Managing Out-of-Control Chronic Gout: Going Beyond Oral Treatments appeared first on Reader's Digest. Do you sometimes have severe, unexplained pain in your joints, particularly in your ...
Gout is due to persistently elevated levels of uric acid (urate) in the blood (hyperuricemia). [2] [5] This occurs from a combination of diet, other health problems, and genetic factors. [1] [2] At high levels, uric acid crystallizes and the crystals deposit in joints, tendons, and surrounding tissues, resulting in an attack of gout. [1]
In general, this effect is achieved by action on the proximal tubule of the kidney. Drugs that reduce blood uric acid are not all uricosurics; blood uric acid can be reduced by other mechanisms (see other Antigout Medications). Uricosurics are often used in the treatment of gout, a disease in which uric acid crystals form deposits in the joints.
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
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