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Randomization is a statistical process in which a random mechanism is employed to select a sample from a population or assign subjects to different groups. [1] [2] [3] The process is crucial in ensuring the random allocation of experimental units or treatment protocols, thereby minimizing selection bias and enhancing the statistical validity. [4]
In the statistical theory of design of experiments, randomization involves randomly allocating the experimental units across the treatment groups.For example, if an experiment compares a new drug against a standard drug, then the patients should be allocated to either the new drug or to the standard drug control using randomization.
An example of an unrandomized design would be to always run 2 replications for the first level, then 2 for the second level, and finally 2 for the third level. To randomize the runs, one way would be to put 6 slips of paper in a box with 2 having level 1, 2 having level 2, and 2 having level 3.
An example would be if the students in the school had numbers attached to their names ranging from 0001 to 1000, and we chose a random starting point, e.g. 0533, and then picked every 10th name thereafter to give us our sample of 100 (starting over with 0003 after reaching 0993).
This does not look random, but it satisfies the definition of random variable. This is useful because it puts deterministic variables and random variables in the same formalism. The discrete uniform distribution, where all elements of a finite set are equally likely. This is the theoretical distribution model for a balanced coin, an unbiased ...
A randomized controlled trial (or randomized control trial; [2] RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices, diagnostic procedures, diets or other medical treatments. [3] [4]
Random assignment or random placement is an experimental technique for assigning human participants or animal subjects to different groups in an experiment (e.g., a treatment group versus a control group) using randomization, such as by a chance procedure (e.g., flipping a coin) or a random number generator. [1]
For example, random assignment in randomized controlled trials helps scientists to test hypotheses, and random numbers or pseudorandom numbers help video games such as video poker. These uses have different levels of requirements , which leads to the use of different methods.