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  2. Naked mole-rat - Wikipedia

    en.wikipedia.org/wiki/Naked_mole-rat

    The Golan Heights blind mole-rat (Spalax golani) and the Judean Mountains blind mole-rat (Spalax judaei) are also resistant to cancer, but by a different mechanism. [ 35 ] In July 2023 a study reported the transference of the gene responsible for HMW-HA from a naked mole rat to mice leading to improved health and an approximate 4.4 percent ...

  3. DNA damage theory of aging - Wikipedia

    en.wikipedia.org/wiki/DNA_damage_theory_of_aging

    The DNA repair transcriptomes of the liver of humans, naked mole-rats and mice were compared. [114] The maximum lifespans of humans, naked mole-rat, and mouse are respectively ~120, 30 and 3 years. The longer-lived species, humans and naked mole rats expressed DNA repair genes, including core genes in several DNA repair pathways, at a higher ...

  4. Disposable soma theory of aging - Wikipedia

    en.wikipedia.org/wiki/Disposable_soma_theory_of...

    However, although these naked mole rats are mammalian, they are highly atypical in terms of aging studies and may not serve as the best model for humans. For example, naked mole rats have a disproportionately high longevity quotient and live in eusocial societies, where breeding is usually designated to a queen. [46]

  5. Meet the naked mole-rat: impervious to pain and cancer, and ...

    www.aol.com/news/meet-naked-mole-rat-impervious...

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  6. Rat Genome Database - Wikipedia

    en.wikipedia.org/wiki/Rat_genome_database

    Gene Annotator: The Gene Annotator or GA tool takes as input a list of gene symbols, RGD IDs, GenBank accession numbers, Ensembl identifiers, or a chromosomal region and retrieves gene orthologs, external database identifiers and ontology annotations for the corresponding genes in RGD. The data can be downloaded into an Excel spreadsheet or ...

  7. DNA repair - Wikipedia

    en.wikipedia.org/wiki/DNA_repair

    The maximum life spans of mice, naked mole-rats and humans are respectively ~3, ~30 and ~129 years. [65] Of these, the shortest lived species, mouse, expresses DNA repair genes, including core genes in several DNA repair pathways, at a lower level than do humans and naked mole rats. [ 65 ]

  8. Radical Life Extension in Humans Is Improbable This Century ...

    www.aol.com/radical-life-extension-humans...

    How long can a human live? Jeanne Calment, the world’s oldest person, offers a ceiling of 122 years and 164 days. But researchers have pondered that the limit could be around 150 years, and ...

  9. Rochelle Buffenstein - Wikipedia

    en.wikipedia.org/wiki/Rochelle_Buffenstein

    Rochelle Buffenstein is an American comparative biologist currently working as Research Professor at the University of Illinois Chicago.Previously, she was a senior principal investigator at Calico Life Sciences, an Alphabet, Inc. funded research and development company investigating the biology that controls aging and lifespan where she used the extraordinarily long-lived cancer resistant ...