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  2. Ondansetron - Wikipedia

    en.wikipedia.org/wiki/Ondansetron

    Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...

  3. 5-HT3 antagonist - Wikipedia

    en.wikipedia.org/wiki/5-HT3_antagonist

    Ondansetron was approved by the U.S. Food and Drug Administration in 1991, and has since become available in several other countries, including the UK, Ireland, Australia, Canada, France and Brazil. As of 2008, ondansetron and granisetron are the only 5-HT 3 antagonists available as a generic drug in the United States. Ondansetron may be given ...

  4. Antiemetic - Wikipedia

    en.wikipedia.org/wiki/Antiemetic

    Ondansetron (Zofran) is administered in an oral tablet form, orally dissolving tablet form, orally dissolving film, sublingual, or in an IV/IM injection. Tropisetron ( Setrovel, Navoban ) can be administered in oral capsules or in injection form.

  5. 5-HT3 receptor - Wikipedia

    en.wikipedia.org/wiki/5-HT3_receptor

    Whereas extracellular domain is the site of action of agonists and competitive antagonists, the transmembrane domain contains the central ion pore, receptor gate, and principle selectivity filter that allows ions to cross the cell membrane. [2]

  6. Serotonin receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Serotonin_receptor_antagonist

    A serotonin antagonist, or serotonin receptor antagonist, is a drug used to inhibit the action of serotonin and serotonergic drugs at serotonin ... Ondansetron ...

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