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Autoimmune hemolytic anemia: Anti-red blood cell antibodies Confirmed 1-3 per 100,000 [89] Immune thrombocytopenia: Anti-platelet antibodies Confirmed 3.3 per 100,000 (adults), 50 per 100,000 (children) [90] Thrombotic thrombocytopenic purpura: ADAMTS13 autoantibodies Confirmed 1-2 per million [91] Antiphospholipid syndrome: Antiphospholipid ...
Mixed autoimmune hemolytic anemia (MAIHA) is a type of autoimmune hemolytic anemia which combines the features of cold sensitive antibody-induced diseases and warm autoimmune hemolytic anemia. The work-up for diagnosis is complex and the condition can be over-diagnosed. [1] [2] [better source needed] People diagnosed with warm autoimmune ...
During this time, they report an overall health state drop – from 88% of patients falling between good and excellent, to 99% falling between good and very poor – and a decrease in health status index by more than half – from 3.8 (on a scale of 1 to 5) pre-illness, to 1.4 at diagnosis.
Drug-induced autoimmune hemolytic anemia also known as Drug-induced immune hemolytic anemia (DIIHA) is a rare cause of hemolytic anemia.It is difficult to differentiate from other forms of anemia which can lead to delays in diagnosis and treatment.
Traumatic hemolytic anemia [2] Impact [2] Macrovascular defects-prostheses [2] Microvascular causes [2] Disseminated intravascular hemolysis [2] Thrombotic thrombocytopenic purpura [2] Typical and atypical hemolytic uremic syndrome [2] Other microvascular abnormalities; Hypersplenism [2] Hemolytic anemia due to toxic effects on the membrane ...
Autoimmune hemolytic anemia: D59.0-D59.1: Autoimmune hemolytic anemia (AIHA) is a type of hemolytic anemia where the body's immune system attacks its own red blood cells (RBCs), leading to their destruction . [28] [29] Types of AIHA include warm autoimmune hemolytic anemia, cold agglutinin disease, and paroxysmal cold hemoglobinuria.
The most common antibody isotype involved in warm antibody AIHA is IgG, though sometimes IgA is found. The IgG antibodies attach to a red blood cell, leaving their F C portion exposed with maximal reactivity at 37 °C (versus cold antibody induced hemolytic anemia whose antibodies only bind red blood cells at low body temperatures, typically 28–31 °C).
Its overall phenotype resembles a combination of autoimmune hemolytic anemia and immune thrombocytopenic purpura. [1] [4] [5] Autoimmune hemolytic anemia is a condition in which the red blood cells that normally carry oxygen are destroyed by an autoimmune process. Immune thrombocytopenic purpura is a condition in which platelets are destroyed ...