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Biotin, synthesized in plants, is essential to plant growth and development. [22] Bacteria also synthesize biotin, [23] and it is thought that bacteria resident in the large intestine may synthesize biotin that is absorbed and utilized by the host organism. [18] Biosynthesis starts from two precursors, alanine and pimeloyl-CoA. These form 7 ...
New Chapter, Inc. is the American manufacturer of the New Chapter brand of vitamins and other organic dietary supplements. Based in Brattleboro, Vermont, the company is a Public Benefit Corporation (PBC) subsidiary of Procter & Gamble. [1]
Biotin-binding affinity can be impaired by chemical labeling of streptavidin, such as with amine-reactive fluorophores; flavidin is a streptavidin mutant without lysine side-chains, which retains good biotin binding characteristics after such fluorescent dye labeling where the dye couples to the amino terminus.
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