enow.com Web Search

Search results

  1. Results from the WOW.Com Content Network
  2. Free-radical theory of aging - Wikipedia

    en.wikipedia.org/wiki/Free-radical_theory_of_aging

    The free radical theory of aging states that organisms age because cells accumulate free radical damage over time. [1] A free radical is any atom or molecule that has a single unpaired electron in an outer shell. [2] While a few free radicals such as melanin are not chemically reactive, most biologically relevant free radicals are highly ...

  3. Reactive oxygen species - Wikipedia

    en.wikipedia.org/wiki/Reactive_oxygen_species

    Reactive oxygen species are implicated in cellular activity to a variety of inflammatory responses including cardiovascular disease. They may also be involved in hearing impairment via cochlear damage induced by elevated sound levels , in ototoxicity of drugs such as cisplatin , and in congenital deafness in both animals and humans.

  4. Mitochondrial theory of ageing - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_theory_of_ageing

    Molecular contributors to ageing (reactive oxygen species, mitochondrial unfolded protein response, mitochondrial metabolites, damage-associated molecular patterns, mitochondrial-derived peptides, mitochondrial membrane) Mitochondria are thought to be organelles that developed from endocytosed bacteria which learned to coexist inside ancient cells.

  5. Biogerontology - Wikipedia

    en.wikipedia.org/wiki/Biogerontology

    Free radicals are reactive molecules produced by cellular and environmental processes, and can damage the elements of the cell such as the cell membrane and DNA and cause irreversible damage. The free-radical theory of aging proposes that this damage cumulatively degrades the biological function of cells and impacts the process of aging. [18]

  6. DNA damage theory of aging - Wikipedia

    en.wikipedia.org/wiki/DNA_damage_theory_of_aging

    Catalase is an enzyme that removes hydrogen peroxide, a reactive oxygen species, and thus limits oxidative DNA damage. In mice, when catalase expression is increased specifically in mitochondria, oxidative DNA damage (8-OHdG) in skeletal muscle is decreased and lifespan is increased by about 20%.

  7. Inflammaging - Wikipedia

    en.wikipedia.org/wiki/Inflammaging

    1] Factors involved in Inflammaging Aging leads to perturbations in cellular homeostasis leading to inflammaging that results in pro-inflammatory cytokine secretion. Inflammaging (also known as inflamm-aging or inflamm-ageing ) is a chronic, sterile, low-grade inflammation that develops with advanced age, in the absence of overt infection, and ...

  8. Doctors Say This Nighttime Behavior Can Be A Sign Of Dementia

    www.aol.com/doctors-nighttime-behavior-sign...

    Fred Kobylarz, MD, is co-director of the Center for Healthy Aging at Rutgers Robert Wood Johnson Medical School. ‘Sundowning’ is a term that refers to behavior changes in people with dementia ...

  9. SOD2 - Wikipedia

    en.wikipedia.org/wiki/SOD2

    Production of reactive oxygen species also increased with cellular age, but by a greater amount in SOD2 mutant cells than in wild-type cells. In the fission yeast Schizosaccharomyces pombe , SOD2 deficiency, drastically increased cellular aging and decreased cell viability in the stationary phase of the growth cycle.