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Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [ 1 ]
Lupus erythematosus may manifest as systemic disease or in a purely cutaneous form also known as incomplete lupus erythematosus. Lupus has four main types: [citation needed] systemic; discoid; drug-induced; neonatal; Of these, systemic lupus erythematosus (also known as SLE) is the most common and serious form.
Childhood-onset systemic lupus erythematosus (i.e., cSLE), also termed juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus, is a form of the chronic inflammatory and autoimmune disease, systemic lupus erythematosus (i.e., SLE), that develops in individuals up to 18 years old. [1]
In fact, it’s so unpredictable that a diagnosis is given only when 4 or more out of eleven diagnostic criteria are met. The first few have to do with the skin and often happen to sun-exposed areas; the first is a Malar rash, meaning a rash over the cheeks that spares the nasolabial folds, sometimes just called a “butterfly rash” and this ...
Two authors have outlines a histopathologic diagnostic criteria for lupus erythematosus panniculitis. The major criteria includes calcification, periseptal or lobular lymphocytic panniculitis , lymphocytic aggregates and lymphoid follicle formation, and hyaline fat necrosis .
This comprises the following two major criteria: systemic lupus erythematosus/discoid lupus erythematosus or response to anti lupus erythematosus therapy or negative cryoglobulin/cold agglutinin studies; additionally, there must be acral skin lesions associated with cold temperature and evidence of lupus erythematosus in skin lesions on ...
Neuropsychiatric systemic lupus erythematosus or NPSLE refers to the neurological and psychiatric manifestations of systemic lupus erythematosus. SLE is a disease in which the immune system attacks the body's own cells and tissues. It can affect various organs or systems of the body.
Some examples of diagnostic criteria, also known as clinical case definitions, are: Amsterdam criteria for hereditary nonpolyposis colorectal cancer; McDonald criteria for multiple sclerosis; ACR criteria for systemic lupus erythematosus; Centor criteria for strep throat