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Congenital blindness is a hereditary disease and can be treated by gene therapy. Visual loss in children or infants can occur either at the prenatal stage (during the time of conception or intrauterine period ) or postnatal stage (immediately after birth). [ 3 ]
Childhood blindness is an important contribution to the national prevalence of the disability of blindness. [3] Blindness in children can be defined as a visual acuity of <3/60 in the eye with better vision of a child under 16 years of age. [4]
Childhood schizophrenia (also known as childhood-onset schizophrenia, and very early-onset schizophrenia) is similar in characteristics of schizophrenia that develops at a later age, but has an onset before the age of 13 years, and is more difficult to diagnose. [3]
Schizophrenia is a mental disorder [17] [7] characterized variously by hallucinations (typically, hearing voices), delusions, disorganized thinking and behavior, [10] and flat or inappropriate affect. [7] Symptoms develop gradually and typically begin during young adulthood and are never resolved.
Leber's congenital amaurosis (LCA) is the most severe and earliest of the inherited retinal dystrophies that cause congenital blindness. It has an incidence of 2-3 per 100,000 births and accounts for 10-18% of cases of congenital blindness among children in blind institutes and 5% of all retinal dystrophies, a figure that is likely to be greater in countries with a greater percentage of ...
Several long-term studies found that individuals born with congenital visual impairment do not develop schizophrenia, suggesting a protective effect. [96] [97] The effects of estrogen in schizophrenia have been studied in view of the association between the onset of menopause in women who develop schizophrenia at this time. Add-on estrogen ...
One reason that Molyneux's Problem could be posed in the first place is the extreme dearth of human subjects who gain vision after extended congenital blindness. In 1971, Alberto Valvo estimated that fewer than twenty cases have been known in the last 1000 years. [6]
During the 1890s and early 1900s, James Hinshelwood, a British ophthalmologist, published a series of articles in medical journals describing similar cases of congenital word blindness, which he defined as "a congenital defect occurring in children with otherwise normal and undamaged brains characterised by a difficulty in learning to read."
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