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Topical clotrimazole is categorized as pregnancy category B. [15] Small amounts of clotrimazole may be absorbed systemically following topical and vaginal administration. However, topical clotrimazole is still considered safe to use to treat yeast infections in pregnant women and is a safer alternative to other antifungals. [15] [16]
Intravaginal (vaginal suppository): butoconazole, clotrimazole, miconazole, nystatin, tioconazole, terconazole. [4] Candidal vulvovaginitis in pregnancy should be treated with intravaginal clotrimazole or nystatin for at least 7 days. [26] All are more or less equally effective. [27] By mouth: ibrexafungerp, fluconazole as a single dose. [4]
A 2017 Cochrane review found waiting generally resulted in better outcomes in those before 37 weeks. [5] Antibiotics may be given for those at risk of Group B streptococcus. [2] Delivery is generally indicated in those with complications, regardless of how far along in pregnancy. [2]
Candidiasis is a fungal infection due to any species of the genus Candida (a yeast). [4] When it affects the mouth, in some countries it is commonly called thrush. [3] Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. [3]
The side effects of oral treatment are significant and people without an infection should not take these drugs. [36] Azoles are the group of antifungals which act on the cell membrane of fungi. They inhibit the enzyme 14-alpha-sterol demethylase, a microsomal CYP, which is required for the biosynthesis of ergosterol for the cytoplasmic membrane.
The typical treatment is topical antifungal cream and anti-inflammatory agents. [3] Specifically, ketoconazole or ciclopirox are effective. [ 10 ] Seborrhoeic dermatitis of the scalp is often treated with shampoo preparations of ketoconazole zinc pyrithione , and selenium , although the latter has been partly discontinued due to concerns of ...
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Miconazole is a widely used topical antifungal medication for the treatment of many fungal infections, namely skin infections, nail infections and vaginal candidiasis. The drug is usually formulated in creams, powders and sprays. However, it is suggested that patients developing acute porphyrias should avoid using this drug.
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