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Osteoarthritis often results in a breakdown of the natural joint fluid that helps the knee move smoothly and absorbs shocks. Hyaluronic acid, the main component in these injections, mimics the ...
Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. Due to a combination of acute stress and chronic fatigue, osteoarthritis directly manifests itself in a wearing away of the articular surface and, in extreme cases, bone can be exposed in the joint.
The cells targeted for the treatment of osteoarthritis are chondrocytes, synoviocytes, and their progenitors. Since the joint capsule is relatively well contained, intra-articular injections are highly successful at delivering the therapeutic gene therapy locally to the target cell types. Treatment of osteoarthritis may be successful via:
Removing this excess material via lavage frequently resolves arthritic knee inflammation or pain. [2] Arthroscopic lavage is one of many procedures available to help reverse the damage of early arthritis. There is, however, controversy about the value of simple lavage and debridement for the older patient with established osteoarthritis. [3]
A doctor may recommend alternatives to surgery for knee issues. ... before they consider surgery for people with severe knee osteoarthritis. ... acid is a natural lubricant that supports the fluid ...
Osteoarthritis typically affects the weight-bearing joints, such as the back, knee and hip. Unlike rheumatoid arthritis, osteoarthritis is most commonly a disease of the elderly. The strongest predictor of osteoarthritis is increased age, likely due to the declining ability of chondrocytes to maintain the structural integrity of cartilage. [69]
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