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  2. Congenital insensitivity to pain - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    Congenital insensitivity to pain (CIP), also known as congenital analgesia, is one or more extraordinarily rare conditions in which a person cannot feel (and has never felt) physical pain. [1] The conditions described here are separate from the HSAN group of disorders, which have more specific signs and cause.

  3. Congenital insensitivity to pain with anhidrosis - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    Since people with this condition are unable to sweat, they are unable to properly regulate their body temperature. [1] Those affected are unable to feel pain and temperature. [2] [3] The absence of pain experienced by people with CIPA puts them at high risk for accidental self-injury. Corneal ulceration occurs due to lack of protective impulses ...

  4. Hereditary sensory and autonomic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Hereditary_sensory_and...

    Additionally, NGFβ signaling plays a role in pain sensation. Mutation of the NGF gene leads to the production of a protein that cannot bind to the receptor and does not transmit signals properly. Without the proper signaling, sensory neurons die and pain sensation is altered, resulting in the inability of people with HSAN5 to feel pain.

  5. Marsili syndrome - Wikipedia

    en.wikipedia.org/wiki/Marsili_syndrome

    The most covered family in the media with this condition is the Italian family reported by Habib et al. in 2018, with various media companies worldwide reporting on the story, these articles often reassure viewers that not feeling pain is not a desirable "superpower", since it can turn dangerous in untreated and unmanaged cases.

  6. Familial dysautonomia - Wikipedia

    en.wikipedia.org/wiki/Familial_dysautonomia

    Familial dysautonomia (FD), also known as Riley–Day syndrome, is a rare, [2] progressive, [3] recessive genetic disorder of the autonomic nervous system [2] that affects the development and survival of sensory, sympathetic, and some parasympathetic neurons in the autonomic and sensory nervous system.

  7. List of abbreviations for diseases and disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_abbreviations_for...

    Diseases and disorders SADS Sudden arrhythmic death syndrome: SARS Severe acute respiratory syndrome: SB Spina bifida: SBMD Sensory-based motor disorder: SBS Shaken baby syndrome: SC Sydenham chorea: SD Saint Vitus's dance (see Sydenham chorea) SDD Sensory discrimination disorder SDS Sudden death syndrome SHF Systolic heart failure: SIDS

  8. Asomatognosia - Wikipedia

    en.wikipedia.org/wiki/Asomatognosia

    In addition to instances of asomatognosia in which patients deny ownership of a specific part, this condition is also associated with the following: anosognosia (unawareness or denial of illness), anosodiaphoria (indifference to illness), autopagnosia (inability to localize and name body parts), and asymbolia for pain (absence of typical reactions to pain).

  9. Hypoesthesia - Wikipedia

    en.wikipedia.org/wiki/Hypoesthesia

    Hypoesthesia is one of the negative sensory symptoms associated with cutaneous sensory disorder (CSD). In this condition, patients have abnormal disagreeable skin sensations that can be due to increased nervous system activity (stinging, itching or burning) or decreased nervous system activity (numbness or hypoesthesia).