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The book that summarized and expanded on the study, Schizophrenia and Genetics: A Twin Study Vantage Point, argued that schizophrenia is a product of several genes acting together, and introduced the techniques of precise analysis in the field of behavioral genetics. [4]
James Shields (21 November 1918 – 20 June 1978) was a Scottish psychiatric geneticist and twin researcher. [1] In the 1960s, he worked with Irving Gottesman on a twin study of schizophrenia at the Medical Research Council Psychiatric Genetics Unit at Maudsley Hospital in London, England.
Irving I. Gottesman (1930–2016), US behavioral geneticist, used twin studies to analyze schizophrenia; Carol W. Greider (born 1961), US molecular biologist, Lasker Award and Nobel Prize for telomeres and telomerase; Jack Greenblatt (20-21st centuries), Molecular geneticist at the University of Toronto
The power of twin designs arises from the fact that twins may be either identical (monozygotic (MZ), i.e. developing from a single fertilized egg and therefore sharing all of their polymorphic alleles) or fraternal (dizygotic (DZ), i.e. developing from two fertilized eggs and therefore sharing on average 50% of their alleles, the same level of genetic similarity found in non-twin siblings).
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Latinos Define Their Identity In Stunning Photo Essay
McGuffin and colleagues re-examined the classic Maudsley schizophrenia study of Gottesman and Shields at a time when there widespread questioning of a genetic component for schizophrenia on the basis that studies until then had used descriptive clinical diagnoses rather than modern operational criteria.
Susie Coughlin was concerned when her daughter struggled with reading skills at her public school. The mom of two was disappointed her district didn't teach phonics as part of its literacy program.