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Serpiginous choroiditis, also known as geographic helicoid peripapillary choroidopathy (GHPC), is a rare, chronic, progressive, and recurrent bilateral inflammatory disease involving the retinal pigment epithelium (RPE), the choriocapillaries, and the choroid. [1] It affects adult men and women equally in the second to seventh decades of life. [2]
In contrast, white dots appear later in the disease stages of birdshot choroidopathy, serpiginous choroiditis, and acute posterior multifocal placoid pigment epitheliopathy. The white dots in these diseases may be present throughout the entire fundus, larger (50 to 500 μm), and tend to clump together.
Serpiginous, first known to be used in the 15th century, is a term from Latin serpere (“to creep”), usually referring to a creeping, snakelike or slowly progressive skin disease. [ 1 ] [ 2 ]
Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina of the eye. It is a form of posterior uveitis.Inflammation of these layers can lead to vision-threatening complications.
For many, the infection starts with cold-like symptoms like a runny nose, sneezing, a low-grade fever and a tickly cough. A painful, full-body cough can develop within a week or two.
But those first migraine warning signs can be subtle and unexpected, including symptoms like difficulty concentrating, sleep disturbances, food cravings, neck pain and yawning.
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Punctate inner choroiditis (PIC) is an inflammatory choroiditis which occurs mainly in young women. Symptoms include blurred vision and scotomata. Yellow lesions are mainly present in the posterior pole and are between 100 and 300 micrometres in size. PIC is one of the so-called White Dot Syndromes.