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Serpiginous choroiditis, also known as geographic helicoid peripapillary choroidopathy (GHPC), is a rare, chronic, progressive, and recurrent bilateral inflammatory disease involving the retinal pigment epithelium (RPE), the choriocapillaries, and the choroid. [1] It affects adult men and women equally in the second to seventh decades of life. [2]
In contrast, white dots appear later in the disease stages of birdshot choroidopathy, serpiginous choroiditis, and acute posterior multifocal placoid pigment epitheliopathy. The white dots in these diseases may be present throughout the entire fundus, larger (50 to 500 μm), and tend to clump together.
Serpiginous, first known to be used in the 15th century, is a term from Latin serpere (“to creep”), usually referring to a creeping, snakelike or slowly progressive skin disease. [ 1 ] [ 2 ] It is used to describe the rash in cutaneous larvae migrans , [ 3 ] erythema annulare centrifugum , [ 4 ] purpura annularis telangiectoides , ringworm ...
The first known name for this condition was "serpiginous ulcer", which dates to 1882. [11] [12] The proper clinical designation for donovanosis is "granuloma inguinale". [5] A granuloma is a nodular type of inflammatory reaction, and inguinale refers to the inguinal region, which is commonly involved in this infection. The disease is commonly ...
Choroideremia (/ k ɒ ˌ r ɔɪ d ɪ ˈ r iː m i ə /; CHM) is a rare, X-linked recessive form of hereditary retinal degeneration that affects roughly 1 in 50,000 males. The disease causes a gradual loss of vision, starting with childhood night blindness, followed by peripheral vision loss and progressing to loss of central vision later in life.
Punctate inner choroiditis (PIC) is an inflammatory choroiditis which occurs mainly in young women. Symptoms include blurred vision and scotomata . Yellow lesions are mainly present in the posterior pole and are between 100 and 300 micrometres in size.
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The prodromal phase may have no symptoms, or may mimic a nonspecific viral infection, marked by flu-like symptoms that typically last for a few days. [6] Fever, headache, nausea, meningismus , dysacusia (discomfort caused by loud noises or a distortion in the quality of the sounds being heard), tinnitus , and/or vertigo may occur.