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The trigeminovascular system (TVS) refers to neurons and their axonal projections within the trigeminal nerve that project to the cranial meninges and meningeal blood vessels [1] [2] residing on the brain's surface. [3]
In neuroanatomy, the trigeminal nerve (lit. triplet nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and chewing; it is the most complex of the cranial nerves.
The first-order neurons from the trigeminal ganglion enter the pons and synapse in the principal (chief sensory) nucleus or spinal trigeminal nucleus.Axons of the second-order neurons cross the midline and terminate in the ventral posteromedial nucleus of the contralateral thalamus (as opposed to the ventral posterolateral nucleus, as in the dorsal column medial lemniscus (DCML) system).
Trigeminal: Both sensory and motor Pons: Three Parts: V 1 (ophthalmic nerve) is located in the superior orbital fissure V 2 (maxillary nerve) is located in the foramen rotundum. V 3 (mandibular nerve) is located in the foramen ovale. Receives sensation from the face, mouth and nasal cavity, and innervates the muscles of mastication. VI Abducens ...
The trigeminal lemniscus contains two main divisions: The ventral trigeminal tract - consists of second-order axons from the spinal trigeminal nucleus. These fibers cross the midline and ascend to the contralateral thalamus. The dorsal trigeminal tract - consists of second-order axons from the principal sensory nucleus of trigeminal nerve ...
An action potential (or nerve impulse) is a transient alteration of the transmembrane voltage (or membrane potential) across the membrane in an excitable cell generated by the activity of voltage-gated ion channels embedded in the membrane. The best known action potentials are pulse-like waves that travel along the axons of neurons.
The trigeminal ganglion contains cell bodies of the pseudo-unipolar sensory neurons of the trigeminal nerve which extend their axons both distally/peripherally into the three divisions of the trigeminal nerve on the one end, and proximally/centrally to the brainstem on the other end; the trigeminal root extends from the trigeminal ganglion to the ventrolateral aspect of the pons.
The dorsal trigeminal tract (also dorsal trigeminothalamic tract, or posterior trigeminothalamic tract) are uncrossed second-order sensory fibers conveying fine (discriminative) touch and pressure information from the dorsomedial division of principal sensory nucleus of trigeminal nerve to the ipsilateral ventral posteromedial nucleus of thalamus.