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Ramón y Cajal's drawing of the cells of the chick cerebellum, from Estructura de los centros nerviosos de las aves, Madrid, 1905. The neuron doctrine is the concept that the nervous system is made up of discrete individual cells, a discovery due to decisive neuro-anatomical work of Santiago Ramón y Cajal and later presented by, among others, H. Waldeyer-Hartz. [1]
Drawing by Camillo Golgi of a hippocampus stained with the silver nitrate method Drawing of a Purkinje cell in the cerebellum cortex done by Santiago Ramón y Cajal, clearly demonstrating the power of Golgi's staining method to reveal fine detail. Golgi's method is a silver staining technique that is used to visualize nervous tissue under light ...
In 2007, sculptures of Severo Ochoa and Santiago Ramón y Cajal created by Víctor Ochoa were unveiled at the Spanish National Research Council central headquarters in Madrid, Spain. [35] Santiago Ramón y Cajal Museum, Ayerbe, Huesca, Spain opened in 2013 and is located in Cajal's childhood home, where he lived with his family for ten years. [36]
Drawing of Purkinje cells (A) and granule cells (B) from pigeon cerebellum by Santiago Ramón y Cajal, 1899.Instituto Santiago Ramón y Cajal, Madrid, Spain. The name granule cell has been used for a number of different types of neurons whose only common feature is that they all have very small cell bodies.
Dendritic spines were first noted by Ramón y Cajal in 1888 by using Golgi's method. Ramón y Cajal was also the first person to propose the physiological role of increasing the receptive surface area of the neuron. The greater the pyramidal cell's surface area, the greater the neuron's ability to process and integrate large amounts of information.
Drawing of the cerebellar cortex, showing axo-axonic synapses (green) formed by Basket cell projections (pink) onto Purkinje cells (blue) at the axon hillock. The axo-axonic synapse in the cerebellar cortex originally appeared in one of the drawings of Santiago Ramón y Cajal in his book published in 1909. [21]
His technique was used by Santiago Ramón y Cajal and led to the formation of the neuron doctrine, the hypothesis that the functional unit of the brain is the neuron. Golgi and Ramón y Cajal shared the Nobel Prize in Physiology or Medicine in 1906 for their extensive observations, descriptions and categorizations of neurons throughout the brain.
This neuron doctrine turned out to be the correct description of the nervous system, whereas the reticular theory was discredited. [1] The proponents of the two contrasting theories, Golgi and Ramón y Cajal were jointly awarded the Nobel Prize in Physiology or Medicine in 1906, "in recognition of their work on the structure of the nervous ...