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Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
In clinical pharmacology, dose refers to the amount of drug administered to a person, and dosage is a fuller description that includes not only the dose (e.g., "500 mg") but also the frequency and duration of the treatment (e.g., "twice a day for one week").
An online version is available, with all drug listings available to view for free. Concise drug monographs form the core of MIMS; these include safety information, details of the active ingredient, presentation, price, indication, dosage and manufacturer. In addition, the book includes drug comparison tables, and summaries of clinical guidance.
The defined daily dose (DDD) is a statistical measure of drug consumption, defined by the World Health Organization (WHO) Collaborating Centre for Drug Statistics Methodology. It is defined in combination with the ATC Code drug classification system for grouping related drugs. The DDD enables comparison of drug usage between different drugs in ...
Specifically, for drug dosing, the patient's length-based dosing zone can be adjusted up one color zone if the child appears overweight. Thus, incorporating a visual estimate of whether the child is overweight provides a simple method to predict actual patient weight that appears to be clinically relevant given the rise in obesity in the U.S ...
Back in 2021, Clinton spoke with PEOPLE about his family's holiday traditions, sharing that he and Hillary usually visit Chelsea and her three kids — Charlotte, 8, Aidan, 6, and Jasper, 3 ...
When healthy, Bieber has been among the best pitchers in baseball, with a 3.02 ERA since 2019 that ranks 15th among MLB starters. However, at age 29, there are also signs beyond the injuries that ...
Another use is in the therapeutic drug monitoring of drugs with a narrow therapeutic index. For example, gentamicin is an antibiotic that can be nephrotoxic (kidney damaging) and ototoxic (hearing damaging); measurement of gentamicin through concentrations in a patient's plasma and calculation of the AUC is used to guide the dosage of this drug ...