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This is an IgG1-based heterodimeric antibody scaffold that consists of two different heavy chains engineered to exclusively assemble into a single molecule, allowing bi-specific binding to two different antigens or drug targets. The Azymetric scaffold is engineered by making amino acid changes in the CH3 region of the constant Fc domain of the ...
The company was founded in 1998 by Jonathan Milner with co-founders professor Tony Kouzarides and David Cleevely, with the idea of making it easier for research scientists to buy antibodies across the web. [5] Milner was a postdoctoral researcher studying the newly discovered breast cancer protein BRCA2 in Kouzarides' Cambridge University ...
Cell Signaling Technology, Inc. (CST) is a privately held company that develops and produces antibodies, ELISA kits, ChIP kits, proteomic kits, and other related reagents used to study the cell signaling pathways that impact human health. CST maintains an in-house research program, particularly in the area of cancer research, and has published ...
Santa Cruz Biotechnology, Inc. (SCBT) is a developer of biological products for medical research, [1] [2] and is one of the world's largest suppliers of antibodies. [3] Santa Cruz Biotechnology headquarters are located in Dallas, Texas, with additional US facilities in Paso Robles, California, [4] and Sun Valley, Idaho.
Creative Biolabs, Inc. is a life-science company which produces and supplies biotech products and services for early drug discovery and development, including various phage display libraries [1] such as pre-made libraries, [2] phage display services, [3] [4] antibody sequencing, [5] and antibody humanization. [6]
Recombinant antibodies are antibody fragments produced by using recombinant antibody coding genes. [1] They mostly consist of a heavy and light chain of the variable region of immunoglobulin . Recombinant antibodies have many advantages in both medical and research applications, which make them a popular subject of exploration and new ...
Invitrogen is one of several brands under the Thermo Fisher Scientific corporation. The product line includes various subbrands of biotechnology products, such as machines and consumables for polymerase chain reaction, reverse transcription, cloning, culturing, stem cell production, cell therapy, regenerative medicine, immunotherapy, transfection, DNA/RNA purification, diagnostic tests ...
BioLegend is a global developer and manufacturer of antibodies and reagents used in biomedical research located in San Diego, California. [1] It was incorporated in June 2002 and has since expanded to include BioLegend Japan KK, where it is partnered with Tomy Digital Biology Co., Ltd. in Tokyo, BioLegend Europe in the United Kingdom, BioLegend GmbH in Germany, and BioLegend UK Ltd in the ...
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