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Ipratropium bromide was patented in 1966, and approved for medical use in 1974. [12] It is on the World Health Organization's List of Essential Medicines, the most important medicines needed in a health system. [13] Ipratropium is available as a generic medication. [3]
Ipratropium bromide/salbutamol, sold under the brand name Combivent among others, is a combination medication used to treat chronic obstructive pulmonary disease (COPD). [1] [4] [5] It contains ipratropium (an anticholinergic) and salbutamol (albuterol, a β 2-adrenergic agonist). [1] Common side effects include sore throat, muscle cramps, and ...
Some examples of anticholinergics are tiotropium (Spiriva) and ipratropium bromide. [citation needed] Tiotropium is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Only available as an inhalant, ipratropium bromide is used in the treatment of asthma and COPD.
Important [5] muscarinic antagonists include atropine, hyoscyamine, hyoscine butylbromide and hydrobromide, ipratropium, tropicamide, cyclopentolate, pirenzepine and scopalamine. Muscarinic antagonists such as ipratropium bromide can also be effective in treating asthma , since acetylcholine is known to cause smooth muscle contraction ...
In the United States, pharmaceutical manufacturers use legal and regulatory strategies to keep inhaler prices artificially high. There has been little innovation in inhaler technology for decades — the most recent drug to be approved by the FDA for treating asthma or COPD via a novel target of action was Ipratropium bromide in 1986.
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Bromide salts are used in hot tubs as mild germicidal agents to generate in situ hypobromite. The bromide ion is antiepileptic and as bromide salt, is used in veterinary medicine in the US. The kidneys excrete bromide ions. The half-life of bromide in the human body (12 days) is long compared with many pharmaceuticals, making dosing challenging ...
An anti-asthmatic agent, also known as an anti-asthma drug, refers to a drug that can aid in airway smooth muscle dilation to allow normal breathing during an asthma attack or reduce inflammation on the airway to decrease airway resistance for asthmatic patients, or both.
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