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Glioblastoma, previously known as glioblastoma multiforme (GBM), is the most aggressive and most common type of cancer that originates in the brain, and has a very poor prognosis for survival. [ 6 ] [ 7 ] [ 8 ] Initial signs and symptoms of glioblastoma are nonspecific. [ 1 ]
Glioblastoma (GBM) is the most common and aggressive malignant brain tumor, accounting for about 15% of all primary malignant brain tumors. ... Symptoms occur due to GBM's disruption of normal ...
The giant-cell glioblastoma is a histological variant of glioblastoma, presenting a prevalence of bizarre, multinucleated (more than 20 nuclei) giant (up to 400 μm diameter) cells. It occasionally shows an abundant stromal reticulin network and presents a high frequency of TP53 gene mutations .
Temozolomide is effective for treating Glioblastoma Multiforme (GBM) compared to radiotherapy alone. [67] A 2013 meta-analysis showed that Temozolomide prolongs survival and delays progression, but is associated with an increase in side effects such as blood complications, fatigue, and infection. [67]
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Glioblastoma multiforme 1 year [199] Ted Kennedy: 1932–2009 United States Senator from Massachusetts Glioblastoma multiforme 15 months [200] Peter Law: 1948–2006 Welsh politician, independent Member of Parliament (MP) and AM. — —
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