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  2. Oxycodone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone

    Oxycodone is used for managing moderate to severe acute or chronic pain when other treatments are not sufficient. [16] It may improve quality of life in certain types of pain. [26] Numerous studies have been completed, and the appropriate use of this compound does improve the quality of life of patients with long term chronic pain syndromes ...

  3. Extended-release morphine - Wikipedia

    en.wikipedia.org/wiki/Extended-release_morphine

    MST Continus is a 12-hour release formula, therefore it is given 2 times per day. It is available in the following doses: 5 mg, 10 mg, 15 mg, 30 mg, 60 mg, 100 mg and 200 mg tablets (equating to between 0.416 mg/hour and 16.67 mg/hour).

  4. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Methadone is different from most opioids because its potency can vary depending on how long it is taken. Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine.

  5. Morphine - Wikipedia

    en.wikipedia.org/wiki/Morphine

    In general, until the synthesis of dihydromorphine (c. 1900), the dihydromorphinone class of opioids (1920s), and oxycodone (1916) and similar drugs, there were no other drugs in the same efficacy range as opium, morphine, and heroin, with synthetics still several years away (pethidine was invented in Germany in 1937) and opioid agonists among ...

  6. Oxymorphone - Wikipedia

    en.wikipedia.org/wiki/Oxymorphone

    Oxymorphone (sold under the brand names Numorphan and Opana among others) is a highly potent opioid analgesic indicated for treatment of severe pain. Pain relief after injection begins after about 5–10 minutes, after oral administration it begins after about 30 minutes, and lasts about 3–4 hours for immediate-release tablets and 12 hours for extended-release tablets. [6]

  7. Oxycodone/naloxone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone/naloxone

    Oxycodone/naloxone was released in 2014 in the United States, [5] in 2006 in Germany, and has been available in some other European countries since 2009. In the United Kingdom, the 10 mg oxycodone / 5 mg naloxone and 20 mg / 10 mg strengths were approved in December 2008, and the 40 mg / 20 mg and 5 mg / 10 mg strengths received approval in ...

  8. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    How long addicts’ commitment to sobriety lasts after they graduate from Recovery Kentucky is “the bigger question,” he said. Another possible reason why University of Kentucky researchers came up with such a high success rate: the survey did not include addicts who quit or who were kicked out during the first few months of the program.

  9. Opioid-induced hyperalgesia - Wikipedia

    en.wikipedia.org/wiki/Opioid-induced_hyperalgesia

    Opioid-induced hyperalgesia (OIH) or opioid-induced abnormal pain sensitivity, also called paradoxical hyperalgesia, is an uncommon condition of generalized pain caused by the long-term use of high dosages of opioids [1] such as morphine, [2] oxycodone, [3] and methadone. [4] [5] OIH is not necessarily confined to the original affected site. [6]