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Pigmentation disorders are disturbances of human skin color. [1] There may be a loss or reduction, which may be related to loss of melanocytes or the inability of melanocytes to produce melanin or transport melanosomes correctly. [1] Most pigmentation disorders involve the underproduction or overproduction of melanin. [2] [3]
Poliosis. Depigmentation of sections of skin and hair in 48-year-old man with vitiligo and poliosis. Poliosis (also called poliosis circumscripta) is the decrease or absence of melanin (or colour) in head hair, eyebrows, eyelashes, or any other hirsute area. It is popularly known as white forelock when it affects hair directly above the forehead.
1% of people [ 4] Vitiligo ( / ˌvɪtɪˈlaɪɡoʊ /) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [ 1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure. [ 5][ 6] Treatment options include topical medications, light therapy ...
Changes in hair colour typically occur naturally as people age, eventually turning the hair grey and then white. This normally begins in the early to mid-twenties in men and late twenties in women. More than 60 percent of Americans have some grey hair by age 40. The age at which greying begins seems almost entirely due to genetics.
Piebaldism refers to the absence of mature melanin-forming cells (melanocytes) in certain areas of the skin and hair. It is a rare autosomal dominant disorder of melanocyte development. [ 2]: 867 Common characteristics include a congenital white forelock, scattered normal pigmented and hypopigmented macules and a triangular shaped depigmented ...
Incontinentia pigmenti. This condition is inherited in an X-linked dominant manner. Incontinentia pigmenti ( IP) is a rare X-linked dominant genetic disorder that affects the skin, hair, teeth, nails and central nervous system. It is named from its appearance under a microscope. [ 1]
Specialty. Dermatology. Albinism is a congenital condition characterized in humans by the partial or complete absence of pigment in the skin, hair and eyes. Albinism is associated with a number of vision defects, such as photophobia, nystagmus, and amblyopia. Lack of skin pigmentation makes for more susceptibility to sunburn and skin cancers.
A variety of human hair colors; from top left, clockwise: black, brown, blonde, white, red. Human hair color is the pigmentation of human hair follicles and shafts due to two types of melanin: eumelanin and pheomelanin. Generally, the more melanin present, the darker the hair. Its tone depends on the ratio of black or brown eumelanin to yellow ...
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