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Nogapendekin alfa inbakicept, sold under the brand name Anktiva, is a fixed-dose combination medication used for the treatment of bladder cancer. [1] It is an interleukin-15 receptor agonist. [1] It is given in combination with Bacillus Calmette-Guérin via intravesical drug delivery. [1]
Bladder cancer is much more common in men than women; around 1.1% of men and 0.27% of women develop bladder cancer. [11] This makes bladder cancer the sixth most common cancer in men, and the seventeenth in women. [136] When women are diagnosed with bladder cancer, they tend to have more advanced disease and consequently a poorer prognosis. [136]
Doxorubicin, sold under the brand name Adriamycin among others, is a chemotherapy medication used to treat cancer. [10] This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. [10] It is often used together with other chemotherapy agents. [10] Doxorubicin is given by injection into a vein. [10]
Use of an inhibitor that blocks the interaction of PD-L1 with the PD-1 receptor can prevent the cancer from evading the immune system in this way. [9] Several PD-1 and PD-L1 inhibitors are being trialled within the clinic for use in advanced melanoma, non-small cell lung cancer, renal cell carcinoma, bladder cancer and Hodgkin lymphoma, amongst ...
It is most commonly used for breast cancer, lung cancer, or colorectal cancer. ... Off-label drugs are used to treat conditions other than those that the drug has been FDA-approved to treat ...
Valrubicin ( N -trifluoroacetyladriamycin-14-valerate, trade name Valstar) is a chemotherapy drug used to treat bladder cancer. Valrubicin is a semisynthetic analog of the anthracycline doxorubicin, and is administered by infusion directly into the bladder . It was originally launched as Valstar in the U.S. in 1999 for intravesical therapy of ...