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The most common causes of peptic ulcers are infection with the germ Helicobacter pylori (H. pylori) and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs). These include ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve).
Treatment for peptic ulcers often leads to ulcer healing. But if your symptoms are severe or if you have them even with treatment, your healthcare professional may suggest endoscopy. This procedure can rule out other possible causes for your symptoms.
Helicobacter pylori (H. pylori) infection occurs when Helicobacter pylori (H. pylori) bacteria infect your stomach. This usually happens during childhood. A common cause of stomach ulcers (peptic ulcers), H. pylori infection may be present in more than half the people in the world.
It's possible to have a peptic ulcer and not have any symptoms, although they may cause stomach pain. In some people, a peptic ulcer isn't identified until they experience symptoms related to a complication from an ulcer, such as bleeding or a hole in the lining of the stomach or bowel.
Causes. Gastrointestinal bleeding can occur either in the upper or lower gastrointestinal tract. It can have a number of causes. Upper GI bleeding. Causes can include: Peptic ulcer. This is the most common cause of upper GI bleeding. Peptic ulcers are sores that develop on the lining of the stomach and upper portion of the small intestine.
The inflammation of gastritis is most often the result of infection with the same bacterium that causes most stomach ulcers or the regular use of certain pain relievers. Drinking too much alcohol also can contribute to gastritis.
Causes of upper GI bleeding can include: Peptic ulcer. This is the most common cause of upper GI bleeding. Peptic ulcers are open sores that develop on the inside lining of your stomach and the upper part of your small intestine.
A dull or burning pain in the stomach could be a peptic ulcer. Find out more about this common, treatable digestive condition.
Stomach acid can break down tissue in the esophagus. This can cause inflammation, bleeding and sometimes an open sore, called an ulcer. Esophagitis can cause pain and make swallowing difficult.
Ulcerative colitis is a type of inflammatory bowel disease (IBD) that causes inflammation and sores, called ulcers, in part of the digestive tract. Ulcerative colitis (UL-sur-uh-tiv koe-LIE-tis) affects the innermost lining of the large intestine, called the colon, and rectum.