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YCT529 is a drug which acts as a potent and selective antagonist of the vitamin A receptor retinoic acid receptor alpha (RAR-α). In studies on mice it produced a 99% reduction in sperm production, and it has proceeded to early stage human clinical trials as a potential male contraceptive.
YourChoice Therapeutics, Inc., for example, started phase one human clinical trials of YCT-529, with the goal of becoming the first hormone-free, reversible male birth control pill. In initial ...
The gel was male birth control. Until this past winter when his participation concluded, Whitehead was a volunteer in a phase 2 trial for the gel. The product — which contains testosterone and a ...
No male birth control product has made it to market, but over the past year, there has been promising early progress on new treatments — including a pill, a gel that’s rubbed onto the skin and ...
Male contraceptives, also known as male birth control, are methods of preventing pregnancy by interrupting the function of sperm. [1] The main forms of male contraception available today are condoms , vasectomy , and withdrawal , which together represented 20% of global contraceptive use in 2019.
The male mice remained infertile for up to 2.5 hours, with some sperm regaining motility 3 hours after receiving the compound. Within 24 hours, the male mice regained full fertility, with no side ...
Fertilysin (WIN 18446) is an experimental drug that was studied as a male contraceptive, but was never marketed. It interferes with testicular production of retinoic acid, [1] which is necessary for spermatogenesis. In studies in male animals including rodents, wolves, cats, and shrews, fertilysin was found to be a safe, effective, and ...
Ongoing research presented at the Endocrine Society’s annual meeting shows promise for a new male contraceptive option. The product, a gel, has shown effectiveness beyond what researchers ...