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Oral leukoplakia is a potentially malignant disorder affecting the oral mucosa. It is defined as "essentially an oral mucosal white/gray lesion that cannot be considered as any other definable lesion." Oral leukoplakia is a gray patch or plaque that develops in the oral cavity and is strongly associated with smoking. [8]
Vocal cord dysfunction (VCD) is a condition affecting the vocal cords. [1] It is characterized by abnormal closure of the vocal folds, which can result in significant difficulties and distress during breathing, particularly during inhalation. [1] Due to the similarity in symptoms, VCD attacks are often mistaken for asthma attacks or laryngospasms.
A common symptom of laryngeal papillomatosis is a change in voice quality. More specifically, hoarseness is observed. [4] [5] As a consequence of the narrowing of the laryngeal or tracheal parts of the airway, shortness of breath, chronic cough and stridor (i.e. noisy breathing which can sound like a whistle or a snore), can be present.
The human vocal cords are roughly 12 – 24 mm in length, and 3–5 mm thick. [9] Histologically, the human vocal cords are a laminated structure composed of five different layers. The vocalis muscle, main body of the vocal cords, is covered by the mucosa, which consists of the epithelium and the lamina propria. [10]
Reinke's edema is the swelling of the vocal cords due to fluid collected within the Reinke's space. [2] First identified by the German anatomist Friedrich B. Reinke in 1895, the Reinke's space is a gelatinous layer of the vocal cord located underneath the outer cells of the vocal cord.
Voice disorders [1] are medical conditions involving abnormal pitch, loudness or quality of the sound produced by the larynx and thereby affecting speech production. These include:
Leukoedema is a blue, grey or white appearance of mucosae, particularly the buccal mucosa (the inside of the cheeks); it may also occur on the mucosa of the larynx or vagina.
Contact granuloma is a condition that develops due to persistent tissue irritation in the posterior larynx. [1] [2] Benign granulomas, not to be confused with other types of granulomas, occur on the vocal process of the vocal folds, where the vocal ligament attaches.