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Oral leukoplakia is a potentially malignant disorder affecting the oral mucosa. It is defined as "essentially an oral mucosal white/gray lesion that cannot be considered as any other definable lesion." Oral leukoplakia is a gray patch or plaque that develops in the oral cavity and is strongly associated with smoking. [8]
Vocal cord dysfunction (VCD) is a condition affecting the vocal cords. [1] It is characterized by abnormal closure of the vocal folds, which can result in significant difficulties and distress during breathing, particularly during inhalation. [1] Due to the similarity in symptoms, VCD attacks are often mistaken for asthma attacks or laryngospasms.
Reinke's edema is the swelling of the vocal cords due to fluid collected within the Reinke's space. [2] First identified by the German anatomist Friedrich B. Reinke in 1895, the Reinke's space is a gelatinous layer of the vocal cord located underneath the outer cells of the vocal cord.
Hyperplastic candidiasis is uncommon, accounting for about 5% of oral candidiasis cases, [8] and is usually chronic and found in adults. The most common site of involvement is the commissural region of the buccal mucosa, usually on both sides of the mouth. [10] Another term for hyperplastic candidiasis is "candidal leukoplakia".
A common symptom of laryngeal papillomatosis is a change in voice quality. More specifically, hoarseness is observed. [4] [5] As a consequence of the narrowing of the laryngeal or tracheal parts of the airway, shortness of breath, chronic cough and stridor (i.e. noisy breathing which can sound like a whistle or a snore), can be present.
The human vocal cords are roughly 12 – 24 mm in length, and 3–5 mm thick. [9] Histologically, the human vocal cords are a laminated structure composed of five different layers. The vocalis muscle, main body of the vocal cords, is covered by the mucosa, which consists of the epithelium and the lamina propria. [10]
Leukoedema is a blue, grey or white appearance of mucosae, particularly the buccal mucosa (the inside of the cheeks); it may also occur on the mucosa of the larynx or vagina.
Treatment of vocal fold nodules usually involves behavioural intervention therapy administered by a speech–language pathologist. In severe cases, surgery to remove the lesions is recommended for best prognosis. [8] [9] In children, vocal fold nodules are more common in males; in adults, they are more common in females. [10] [5]