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Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. [25]
The growing spread of counterfeit Botox has horrified Dr. Lavanya Krishnan, a board-certified dermatologist in San Francisco who founded the practice Arya Derm and has been following the FDA and ...
The request comes after the advocacy group analyzed over 5,400 reports of deaths, life-threatening events and other serious side effect related to Botox and rival toxin-based wrinkle treatments ...
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C. botulinum is a Gram-positive, rod-shaped, spore-forming bacterium. [1] It is an obligate anaerobe, the organism survives in an environment that lacks oxygen.However, C. botulinum tolerates traces of oxygen due to the enzyme superoxide dismutase, which is an important antioxidant defense in nearly all cells exposed to oxygen. [7]
The opposite of an indication is a contraindication, [4] a reason to withhold a certain medical treatment because the risks of treatment clearly outweigh the benefits. In the United States, indications for prescription drugs are approved by the FDA. Indications are included in the Indications and Usage section of the Prescribing Information.
There is no indication that authentic Botox, made by the drugmaker AbbVie, is linked to any of the illnesses. That product, the FDA said, "should be considered safe and effective for its intended ...
By blocking nerves from sending signals to the muscle to contract, Botox essentially paralyzes the muscles temporarily. After working-out techniques for preparing the toxin and assuring its sterility, potency, and safety, Scott was granted FDA approval for investigational use, and began manufacturing it in his San Francisco lab.
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